Febrile temperature causes transcriptional downregulation of <i>Plasmodium falciparum</i> Sirtuins through Hsp90?dependent epigenetic modification

Sirtuins in Epigenetic Regulation

Causes of Febrile Seizures

This study was conducted to evaluate the etiologies of pyrexia in children with first febrile seizures using a prospectively recorded medical protocol, bacterial culture, and serologic tests for human herpesvirus-6 (HHV-6), dengue virus and Japanese B encephalitis (JE) virus. Of 82 children with first febrile seizures, who were between 3 months and 3 years old and had been admitted to Bhumibol ...

Febrile Convulsions in Children: Demographic Features, Causes and Seasonal Pattern

Background and Objectives: Febrile convulsion (FC) is the most common seizure disorder in childhood period. Some studies have suggested association between seasons and occurrence of FC. This study was designed to determine demographic features, causes and seasonal variations in cases with FC. Method: In this descriptive, cross sectional study, 282 children 6- 60 months with FC were admitted to ...

Epigenetic Modification of Plant Chromatin

Based on the analysis of 20 different monocot and eudicot species, we propose that the centromeric distribution of the phosphorylated histone H2AThr120 is evolutionary highly conserved across species with monoand holocentric chromosomes. Therefore, antibodies recognizing the phosphorylated threonine 120 of the histone H2A can serve as a universal marker for the cytological detection of centrome...

Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus.

Posttranslational modifications of transcription factors provide alternate protein interaction platforms that lead to varied downstream effects. We have investigated how the acetylation of EKLF plays a role in its ability to alter the beta-like globin locus chromatin structure and activate transcription of the adult beta-globin gene. By establishing an EKLF-null erythroid line whose closed beta...